Basic Information
| LncRNA/CircRNA Name | CRNDE |
| Synonyms | CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5 |
| Region | GRCh38_16:54845189-54929189 |
| Ensemble | ENSG00000245694 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | Microarray, qPCR etc. |
| Sample | ovarian cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | We have shown that the elevated level of CRNDE transcripts significantly increases the risk of death and recurrence in ovarian cancer patients. Elevated levels of two different CRNDE transcripts were a negative prognostic factor; they increased the risk of death and recurrence in the group of patients treated with TP, but not PC (DNA-damaging agents only). |
| Pubmed ID | 26556866 |
| Year | 2015 |
| Title | The putative oncogene, CRNDE, is a negative prognostic factor in ovarian cancer patients. |
External Links
| Links for CRNDE | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |