Basic Information
| LncRNA/CircRNA Name | CRNDE |
| Synonyms | CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5 |
| Region | GRCh38_16:54845189-54929189 |
| Ensemble | ENSG00000245694 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | qPCR, Luciferase reporter assay, Western blot assay etc. |
| Sample | cell lines (BCPAP, KTC-1, K1) |
| Expression Pattern | up-regulated |
| Function Description | In the present study, the main findings showed CRNDE was up-regulated in the PTC tissues and PTC cell lines, and overexpression of CRNDE promoted PTC cell proliferation, invasion and migration, and downregulation of CRNDE exerted suppressive effects on PTC cell proliferation, invasion and migration. |
| Pubmed ID | 29299168 |
| Year | 2017 |
| Title | LncRNA CRNDE promotes cell proliferation, invasion and migration by competitively binding miR-384 in papillary thyroid cancer |
External Links
| Links for CRNDE | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |