Basic Information
| LncRNA/CircRNA Name | CDKN2B-AS1 |
| Synonyms | NA |
| Region | GRCh38_9:21994778-22121097 |
| Ensemble | ENSG00000240498 |
| Refseq | NR_003529 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | PCR, Western blot |
| Sample | OS tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | CDKN2B-AS1 was found to be markedly up-regulated in OS tissues and cell lines.Loss-of-function of CDKN2B-AS1 leaded to inhibited cell proliferation and induced cell cycle G0/G1 phase arrest. |
| Pubmed ID | 31724892 |
| Year | 2020 |
| Title | CDKN2B-AS1 Exerts Oncogenic Role in Osteosarcoma by Promoting Cell Proliferation and Epithelial to Mesenchymal Transition |
External Links
| Links for CDKN2B-AS1 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |