Basic Information
| LncRNA/CircRNA Name | ADAMTS9-AS2 |
| Synonyms | lncADAMTS9-AS2 |
| Region | GRCh38_3:64684909-65011468 |
| Ensemble | ENSG00000241684 |
| Refseq | NR_038264 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot |
| Sample | GC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | overexpression of ADAMTS9-AS2 could up-regulate the expression of SPOP,thus suppressing cell growth, proliferation, promote apoptosis and block cell cycle progression of GC and spheroid formation of tumor-sphere cells, which suggested that ADAMTS9-AS2 played a crucial role in inhibiting GC progression by targeting SPOP. |
| Pubmed ID | 32160650 |
| Year | 2020 |
| Title | LncRNA ADAMTS9-AS2 suppresses the proliferation of gastric cancer cells and the tumorigenicity of cancer stem cells through regulating SPOP |
External Links
| Links for ADAMTS9-AS2 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |