Basic Information
| LncRNA/CircRNA Name | CCAT2 |
| Synonyms | CCAT2, LINC00873, NCCP1 |
| Region | GRCh38_8:127400399-127402150 |
| Ensemble | ENSG00000280997 |
| Refseq | NR_109834 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | autophagy/apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR |
| Sample | breast cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | significant inverse correlations were found between CCAT2 expression and stage, as well as lymph node involvement. Besides, a significant inverse correlation was found between the relative MYC expression in tumor tissues compared with their corresponding ANCTs and disease stage.CCAT2 expression level was suggested as a predictor of metastasis and poor survival for a particular subgroup of breast cancer patients. |
| Pubmed ID | 28480695 |
| Year | 2017 |
| Title | Expression Study and Clinical Correlations of MYC and CCAT2 in Breast Cancer Patients |
External Links
| Links for CCAT2 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |