Basic Information
| LncRNA/CircRNA Name | CCAT2 |
| Synonyms | CCAT2, LINC00873, NCCP1 |
| Region | GRCh38_8:127400399-127402150 |
| Ensemble | ENSG00000280997 |
| Refseq | NR_109834 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | small cell lung cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Cell proliferation assay, Cell migration and invasion assay etc. |
| Sample | SCLC tissues, cell lines (DMS-53, H446, 16HBE) |
| Expression Pattern | up-regulated |
| Function Description | CCAT2 expression was elevated in SCLC tissues and cell lines, and correlated with malignant status and poor prognosis of SCLC patients. Furthermore, knockdown of CCAT2 expression effectively suppressed SCLC cell growth and metastasis in vitro. |
| Pubmed ID | 27470400 |
| Year | 2016 |
| Title | LncRNA CCAT2 predicts poor prognosis and regulates growth and metastasis in small cell lung cancer. |
External Links
| Links for CCAT2 | GenBank HGNC NONCODE |
| Links for small cell lung cancer | OMIM COSMIC |