Basic Information
| LncRNA/CircRNA Name | CCAT2 |
| Synonyms | CCAT2, LINC00873, NCCP1 |
| Region | GRCh38_8:127400399-127402150 |
| Ensemble | ENSG00000280997 |
| Refseq | NR_109834 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, RNAi, Flow cytometry assay, Cell proliferation assay etc. |
| Sample | cell lines (HeLa, CaSki, and SiHa) |
| Expression Pattern | down-regulated |
| Function Description | CCK8 assay showed that CCAT2 knockdown inhibited cell proliferation in HeLa, CaSki, and SiHa cells. The flow cytometry confirmed the results that knockdown of CCAT2 could induce cervical cancer cells cycle G1 phase arrestment and trigger the cells apoptosis |
| Pubmed ID | 26983975 |
| Year | 2016 |
| Title | Roles of Long Non-Coding RNA CCAT2 in Cervical Cancer Cell Growth and Apoptosis |
External Links
| Links for CCAT2 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |