Basic Information
| LncRNA/CircRNA Name | CCAT1 |
| Synonyms | CCAT1, CARLo-5, onco-lncRNA-40 |
| Region | GRCh38_8:127207382-127219268 |
| Ensemble | ENSG00000247844 |
| Refseq | NR_108049 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR |
| Sample | ovarian cancer tissues, cell lines (OVCAR-8 and SKOV-3, OMC685, IOSE386) |
| Expression Pattern | up-regulated |
| Function Description | the expression of lncRNA CCAT1 was closely related to prognosis, tumor size, and lymph node metastasis. lncRNA CCAT1 could sponge miR-1290 in ovarian cancer.high expression of lncRNA CCAT1 could be used as an indicator of the survival time of OC patients. |
| Pubmed ID | 29424889 |
| Year | 2018 |
| Title | LncRNA colon cancer-associated transcript 1 (CCAT1) promotes proliferation and metastasis of ovarian cancer via miR-1290. |
External Links
| Links for CCAT1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |