Basic Information
| LncRNA/CircRNA Name | CCAT1 |
| Synonyms | CCAT1, CARLo-5, onco-lncRNA-40 |
| Region | GRCh38_8:127207382-127219268 |
| Ensemble | ENSG00000247844 |
| Refseq | NR_108049 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | gastric cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | AGS human gastric carcinoma cell line showed an elevated level of CCAT1 expression. Expression levels of CCAT1 were approximately 10.8 fold higher in GC samples than in samples taken from the negative control group. Interestingly, CCAT1 expression was significantly overexpressed in adjacent normal tissues when compared to the negative control group. Tissues obtained from recurrent GC cases showed the highest expression levels. Expression levels increased with tumor stage, however this did not reach statistical significance. |
| Pubmed ID | 25561974 |
| Year | 2014 |
| Title | Colon Cancer Associated Transcript-1 (CCAT1) Expression in Adenocarcinoma of the Stomach. |
External Links
| Links for CCAT1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |