Basic Information
| LncRNA/CircRNA Name | circ_0001895 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR |
| Sample | gastric cancer tissues and their adjacent non-tumorous tissues, Normal human gastric mucosa epithelial cell line (GES-1) and five gastric cancer cell lines (AGS, BGC-823, HGC27, MGC-803, and SGC-7901) |
| Expression Pattern | down-regulated |
| Function Description | Hsa_circ_0001895 expression levels in five detected gastric cancer cell lines (AGS, BGC-823, HGC-27, MGC-803, and SGC-7901) were all significantly downregulated than those in normal gastric epithelial GES-1 cells. Besides, compared with healthy control tissues, it was downregulated not only in 69.8% (67/96) gastric cancer tissues but also in gastric precancerous lesions. Moreover, hsa_circ_0001895 expression levels were significantly correlated with cell differentiation, Borrmann type, and tissue carcino-embryonic antigen expression. |
| Pubmed ID | 28443463 |
| Year | 2017 |
| Title | Decreased expression of hsa_circ_0001895 in human gastric cancer and its clinical significances |
External Links
| Links for circ_0001895 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |