Basic Information
| LncRNA/CircRNA Name | CCAT1 |
| Synonyms | CCAT1, CARLo-5, onco-lncRNA-40 |
| Region | GRCh38_8:127207382-127219268 |
| Ensemble | ENSG00000247844 |
| Refseq | NR_108049 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qPCR, ISH etc. |
| Sample | colonic adenoma-carcinoma tissues |
| Expression Pattern | up-regulated |
| Function Description | CCAT1 is up-regulated across the colon adenoma-carcinoma sequence. This up-regulation is evident in pre-malignant conditions and through all disease stages, including advanced metastatic disease suggesting a role in both tumorigenesis and the metastatic process. |
| Pubmed ID | 23594791 |
| Year | 2015 |
| Title | Differential expression of colon cancer associated transcript1 (CCAT1) along the colonic adenoma-carcinoma sequence. |
External Links
| Links for CCAT1 | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |