Basic Information
| LncRNA/CircRNA Name | circ_0032462 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR, RNAi, other |
| Sample | osteosarcoma cell lines MG63, U2OS, 143B, HOS |
| Expression Pattern | up-regulated |
| Function Description | Ultimately, we found cell adhesion molecule 1 (CADM1) gene was not only a co-expression mRNA of the three mRNA expression profiles of OS, but also are predicted to be regulated by hsa_circ_0032462, hsa_circ_0028173, hsa_circ_0005909 by functioning as miRNAs 'Sponge' in human osteosarcoma. These over-expressed circRNAs may result in the over expression of CADM1 which promote the development of OS. We envision this discovery of these important moleculars, incuding hsa_circ_0032462, hsa_circ_0028173, hsa_circ_0005909 and CADM1 may lead to further development of new concepts, thus allowing for more opportunities in diagnosis and therapy of OS. |
| Pubmed ID | 30153287 |
| Year | 2018 |
| Title | Circular RNAs hsa_circ_0032462, hsa_circ_0028173, hsa_circ_0005909 Are Predicted to Promote CADM1 Expression by Functioning as miRNAs Sponge in Human Osteosarcoma |
External Links
| Links for circ_0032462 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |