Basic Information
| LncRNA/CircRNA Name | circ_001242 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | qPCR, other |
| Sample | OSCC tissues and cell lines (SCC9, SCC15,SCC25, and CAL27) |
| Expression Pattern | down-regulated |
| Function Description | Hsa_circ_001242 was significantly downregulated in OSCC tissues compared to paired adjacent normal tissues (P < 0.001). Hsa_circ_001242 expression levels were significantly downregulated in four OSCC cell lines (SCC-9, SCC-15, SCC25, and CAL-27) than in human normal oral keratinocyte (HOK) cell lines. Moreover, the expression level of hsa_circ_001242 was negatively correlated with tumor size and T stage (P < 0.05). The area under the ROC curve was 0.784. |
| Pubmed ID | 30069275 |
| Year | 2018 |
| Title | Clinical Significance of the Decreased Expression of hsa_circ_001242 in Oral Squamous Cell Carcinoma |
External Links
| Links for circ_001242 | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |