Basic Information
| LncRNA/CircRNA Name | circ_0008344 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qPCR, Microarray, other |
| Sample | glioblastoma tissues and cell lines (U87 and U251) |
| Expression Pattern | up-regulated |
| Function Description | Hsa_circ_0008344, among the top differentially expressed circRNAs, was significantly upregulated in IDH1 wild-type glioblastoma. Further in vitro studies showed that knockdown of hsa_circ_0008344 suppressed glioblastoma cell proliferation, colony formation, migration, and invasion, but increased cell apoptotic rate. |
| Pubmed ID | 29687495 |
| Year | 2018 |
| Title | Circular RNA hsa_circ_0008344 Regulates Glioblastoma Cell Proliferation, Migration, Invasion, and Apoptosis |
External Links
| Links for circ_0008344 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |