Basic Information
| LncRNA/CircRNA Name | circ_102231 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | Lung Cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, other |
| Sample | lung cancer tissues and cell lines BEAS-2B, and A549 |
| Expression Pattern | up-regulated |
| Function Description | QRT-PCR showed that circRNA_102231 expression was significantly upregulated in LAC tissues and associated with the advanced TNM stage, lymph node metastasis, and poor overall survival of lung cancer patients. The area under the receiver operating characteristic curve (ROC) was 0.897. in addition, function assays showed that circRNA_102231 inhibition significantly suppressed lung cancer cells proliferation and invasion ability in vitro. |
| Pubmed ID | 29602132 |
| Year | 2018 |
| Title | Increased Expression of circRNA_102231 in Lung Cancer and Its Clinical Significance |
External Links
| Links for circ_102231 | GenBank HGNC NONCODE |
| Links for Lung Cancer | OMIM COSMIC |