Basic Information
| LncRNA/CircRNA Name | circ-0067934 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | RT??PCR, Cell proliferation assay, Colony formation assay |
| Sample | NSCLC tissues, NSCLC cell lines (A549, H1299, SK??ES??, PC??) and normal bronchial epithelial cell line (BEAS??B) |
| Expression Pattern | up-regulated |
| Function Description | the expression levels of circ 0067934 were significantly increased in non-small cell lung cancer (NSCLC) tissues and NSCLC cells compared with that in adjacent normal tissues and a normal human bronchial epithelium cell line. The results demonstrated that the proliferative ability was significantly inhibited when circ-0067934 was knocked down in NSCLC cells. Therefore, these results indicated that circ-0067934 may be a predictive marker for the prognosis of NSCLC and a target for the treatment of the disease. |
| Pubmed ID | 30344708 |
| Year | 2018 |
| Title | Overexpression of circ??067934 is associated with increased cellular proliferation and the prognosis of non??mall cell lung cancer |
External Links
| Links for circ-0067934 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |