Basic Information
| LncRNA/CircRNA Name | 91H |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, RNAi etc. |
| Sample | CRC tissues, cell lines (HCT8, HT29, HCT116, SW620 etc.) |
| Expression Pattern | up-regulated |
| Function Description | 91H was significantly overexpressed in cancerous tissue and CRC cell lines compared with adjacent normal tissue and a normal human intestinal epithelial cell line. Moreover, 91H overexpression was closely associated with distant metastasis and poor prognosis in patients with CRC, except for CNV of 91H. Multivariate analysis indicated that 91H expression was an independent prognostic indicator, as well as distant metastasis. 91H played an important role in the molecular etiology of CRC and might be regarded as a novel prognosis indicator in patients with CRC. |
| Pubmed ID | 25058480 |
| Year | 2014 |
| Title | Up-regulation of 91H promotes tumor metastasis and predicts poor prognosis for patients with colorectal cancer. |
External Links
| Links for 91H | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |